EC Number   |
Subunits |
Reference |
|---|
   2.3.1.297 | ? |
x * 42000, glycosylated enzyme, SDS-PAGE, x * 37000, deglycosylated enzyme, SDS-PAGE |
-, 736217 |
| 2.3.1.297 | ? |
x * 46100, about, isozyme LASS3, sequence calculation, x * 50000, about, isozyme LASS3-long, sequence calculation |
752701 |
| 2.3.1.297 | dimer |
dimer CerS activity can be modulated by dimer formation. CerS2 activity is enhanced by co-expression with a catalytically active form of CerS5 or CerS6. CerS dimers are formed rapidly upon stimulation of ceramide synthesis |
754101 |
| 2.3.1.297 | heterotrimer |
subunits Lac1p, Lag1p, and Lip1p |
-, 753414 |
| 2.3.1.297 | More |
Lag1p, Lac1p and Lip1p comprise the ceramide synthase. Lag1p/Lac1p interacting protein, 28 kDa, Lip1p is an essential component of the ceramide synthase, which forms a heteromeric complex with Lac1p and Lag1p. Lip1p is required for ceramide synthesis in vivo and in vitro. It is possible that Lip1p is modified by O-linked glycosylation. Its short, highly charged N-terminus is cytoplasmic and dispensible for ceramide synthase activity |
-, 753414 |
