EC Number   |
Subunits |
Reference |
|---|
    2.3.1.24 | ? |
x * 44800, SDS-PAGE |
752700 |
| 2.3.1.24 | ? |
x * 50000, recombinant FLAG3-tagged CerS5, SDS-PAGE |
752796 |
| 2.3.1.24 | ? |
x * 62000 + x * 72000, SDS-PAGE |
486668 |
| 2.3.1.24 | dimer |
CerS activity can be modulated by dimer formation. CerS5 activity is inhibited in a dominant-negative fashion by co-expression with catalytically inactive CerS5. CerS dimers are formed rapidly upon stimulation of ceramide synthesis |
754101 |
| 2.3.1.24 | More |
Lass family members contain four to seven predicted transmembrane domains, a catalytic Lag1 motif and most an N-terminal domain showing sequence homology to DNA-binding homeodomains (Hox domain) |
753417 |
| 2.3.1.24 | tetramer |
4 * 62000-72000, SDS-PAGE |
754575 |
