EC Number   |
Substrates |
Organism |
Products  |
Reversibility |
|---|
   6.2.1.54 | ATP + D-alanine |
- |
Bacillus cereus |
(D-alanyl)adenylate + diphosphate |
- |
? |
| 6.2.1.54 | ATP + D-alanine |
- |
Bacillus cereus DSM 31 |
(D-alanyl)adenylate + diphosphate |
- |
? |
| 6.2.1.54 | ATP + D-2-amino butyric acid + diphosphate |
activity and specificity of DltA is investigated using the ATP-pyrophosphate exchange assay. Enzyme shows only minor activity 13% with D-amino butyric acid |
Bacillus subtilis |
? |
- |
? |
| 6.2.1.54 | ATP + D-Ala + diphosphate |
- |
Bacillus cereus |
? |
- |
? |
| 6.2.1.54 | ATP + D-Ala + diphosphate |
activity and specificity of DltA is investigated using the ATP-pyrophosphate exchange assay. Enzyme is highly specific for cognate D-Ala substrate |
Bacillus subtilis |
? |
- |
? |
| 6.2.1.54 | ATP + D-Ser + diphosphate |
activity and specificity of DltA is investigated using the ATP-pyrophosphate exchange assay. Enzyme shows only minor activity 13% with D-Ser |
Bacillus subtilis |
? |
- |
? |
| 6.2.1.54 | ATP + L-Ala + diphosphate |
- |
Bacillus cereus |
? |
- |
? |
| 6.2.1.54 | D-Alanine + ATP + ? |
biosynthesis of D-alanyl-lipoteichoic acid |
Lacticaseibacillus casei |
? |
- |
? |
| 6.2.1.54 | more |
the enzyme is required for incorporation of D-alanine in teichoic acids in Gram-positive bacteria, confering resistance to cationic antimicrobial peptides nisin and gallidermin in Streptococcus pneumoniae, enzymes of D-alanine metabolism are encoded in the dltA operon, a functional dlt operon confers resistance to nisin and gallidermin |
Streptococcus pneumoniae |
? |
- |
? |
| 6.2.1.54 | more |
the ATP and D-alanine substrates of the adenylation reaction are incorporated when the DltA enzyme cycles through its thiolation conformation |
Bacillus cereus |
? |
- |
? |
