EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.6.1.60 | more |
diadenosine tetraphosphate and diadenosine triphosphate, adenosine nucleotides, diphosphoinositol polyphosphate and phosphoribosyl pyrophosphate are not hydrolyzed |
Arabidopsis thaliana |
? |
- |
? |
3.6.1.60 | more |
no activity with P1,P4-bis(5'-adenosyl)tetraphosphate or other dinucleotides, mononucleotides, nucleotide sugars, or nucleotide alcohols |
Saccharomyces cerevisiae |
? |
- |
? |
3.6.1.60 | more |
the enzyme also catalyses the hydrolysis of diphosphoinositol pentakisphosphate |
Homo sapiens |
? |
- |
? |
3.6.1.60 | more |
endopolyphosphatase activity is analyzed by the decrease in polyphosphate chain length (polyphosphate208 and polyphosphate15) |
Saccharomyces cerevisiae |
? |
- |
- |
3.6.1.60 | P1,P4-bis(5'-adenosyl)tetraphosphate + H2O |
weak activity |
Homo sapiens |
ATP + AMP |
- |
? |
3.6.1.60 | P1,P5-bis(5'-adenosyl)pentaphosphate + H2O |
marked preference for adenine over guanine nucleotides. The enzyme controls intracellular P1,P5-bis(5'-adenosyl)pentaphosphate and P1,P6-bis(5'-adenosyl)hexaphosphate levels |
Homo sapiens |
adenosine 5'-tetraphosphate + AMP |
- |
? |
3.6.1.60 | P1,P5-bis(5'-adenosyl)pentaphosphate + H2O |
the function of the enzyme may be to eliminate potentially toxic dinucleoside polyphosphates during sporulation |
Saccharomyces cerevisiae |
adenosine 5'-tetraphosphate + AMP |
- |
? |
3.6.1.60 | P1,P5-bis(5'-adenosyl)pentaphosphate + H2O |
hydrolysis of P1,P5-bis(5'-adenosyl)pentaphosphate yields predominantly AMP and adenosine tetraphosphate (96%) |
Saccharomyces cerevisiae |
adenosine 5'-tetraphosphate + AMP |
- |
? |
3.6.1.60 | P1,P5-bis(5'-adenosyl)pentaphosphate + H2O |
marked preference for adenine over guanine nucleotides. The most rapidly metabolised substrate appears to be P1,P5-bis(5'-adenosyl)pentaphosphate, although P1,P6-bis(5'-adenosyl)hexaphosphate is bound with higher affinity |
Homo sapiens |
adenosine 5'-tetraphosphate + AMP |
- |
? |
3.6.1.60 | P1,P5-bis(5'-adenosyl)pentaphosphate + H2O |
P1,P5-bis(5'-adenosyl)pentaphosphate is hydrolyzed at 40% of the activity compared to P1,P6-bis(5'-adenosyl)hexaphosphate |
Arabidopsis thaliana |
adenosine 5'-tetraphosphate + AMP |
- |
? |