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Results 1 - 10 of 34 > >>
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.365-methylcytosine in single-stranded DNA + H2O Apobec1 has 5-methylcytosine deaminase activity, resulting in a thymine base opposite a guanine. If this mismatch is repaired, a methylated cytosine is replaced by an unmethylated one. If it is not repaired, it results in a cytosine -> thymine transition mutation. Apobec1, and perhaps other members of this protein family play a role in epigenetic reprogramming Rattus norvegicus thymine in single-stranded DNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in RNA + H2O murine APOBEC1 is a hypermutator of both RNA and ssDNA in vivo Mus musculus uracil in RNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in RNA + H2O transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3' untranslated regions, a molecular mechanism that suggests additional roles for APOBEC1 beyond its function in apolipoprotein regulation Mus musculus uracil in RNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in RNA + H2O APOBEC1 site-specifically edits many mRNA transcripts other than apoB in small intestine enterocytes. Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA editing targets in transcript 3' untranslated regions Mus musculus uracil in RNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in RNA + H2O murine APOBEC1 is able to hyperdeaminate cytidine residues in murine leukemia virus genomic RNA. In vitro murine APOBEC1 can extensively edit viral RNA, while human APOBEC1 cannot Mus musculus uracil in RNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in single-stranded DNA + H2O murine APOBEC1 is a hypermutator of both RNA and ssDNA in vivo Mus musculus uracil in single-stranded DNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in single-stranded DNA + H2O ssDNA hyperediting of an infectious exogenous gammaretrovirus, the Friend–murine leukemia virus, by murine APOBEC1 Mus musculus uracil in single-stranded DNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine in single-stranded DNA + H2O when expressed in bacteria, APOBEC1 can deaminate cytosine in DNA. Its activity on DNA is specific for single-stranded DNA and exhibits dependence on local sequence context Rattus norvegicus uracil in single-stranded DNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine6666 in apolipoprotein B mRNA + H2O - Homo sapiens uracil6666 in apolipoprotein B mRNA + NH3 - ?
Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.36cytosine6666 in apolipoprotein B mRNA + H2O - Mus musculus uracil6666 in apolipoprotein B mRNA + NH3 - ?
Results 1 - 10 of 34 > >>