EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   3.4.21.61 | L-pyroglutamyl-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O |
- |
Aeromonas sobria |
L-pyroglutamyl-Arg-Thr-Lys-Arg + 7-amino-4-methyl-coumarin |
- |
? |
| 3.4.21.61 | more |
FRETS-25Xaa libraries as substrates. Best FRETS contains Lys at position Xaa (FRETS-25K). No cleavage of succinyl-Ala-Ala-Pro-Phe-4-methylylcoumaryl-7-amide, t-butyloxycarbonyl-Gly-Arg-Arg-4-methylylcoumaryl-7-amide, Z-His-Glu-Lys-4-methylylcoumaryl-7-amide, and t-butyloxycarbonyl-Phe-Ser-Arg-4-methylylcoumaryl-7-amide |
Aeromonas sobria |
? |
- |
? |
| 3.4.21.61 | prekallikrein |
cleaved into four fragments by ASP, protein cleaved at specific sequences |
Aeromonas sobria |
? |
- |
? |
| 3.4.21.61 | t-butyloxycarbonyl-Arg-Val-Arg-Arg-4-methylcoumaryl-7-amide + H2O |
- |
Aeromonas sobria |
t-butyloxycarbonyl-Arg-Val-Arg-Arg + 7-amino-4-methyl-coumarin |
- |
? |
| 3.4.21.61 | t-butyloxycarbonyl-Glu-Lys-Lys-4-methylcoumaryl-7-amide + H2O |
best substrate |
Aeromonas sobria |
t-butyloxycarbonyl-Glu-Lys-Lys + 7-amino-4-methyl-coumarin |
- |
? |
| 3.4.21.61 | t-butyloxycarbonyl-Gly-Lys-Arg-4-methylcoumaryl-7-amide + H2O |
- |
Aeromonas sobria |
t-butyloxycarbonyl-Gly-Lys-Arg + 7-amino-4-methyl-coumarin |
- |
? |
| 3.4.21.61 | Dpy-5 procollagen + H2O |
- |
Caenorhabditis elegans |
? |
- |
? |
| 3.4.21.61 | low density lipoprotein receptor-related protein 1 + H2O |
degradation |
Cricetulus griseus |
? |
- |
? |
| 3.4.21.61 | low density lipoprotein receptor-related protein 1 + H2O |
the enzyme acts on the extracellular domain of the receptor molecule |
Cricetulus griseus |
? |
- |
? |
| 3.4.21.61 | corin + H2O |
activating processing of corin by enzyme PCSK6 |
Homo sapiens |
? |
- |
? |
