EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   3.1.26.3 | Aa-[16S[micro-hp]RNA] + H2O |
structures of the Aquifex pre-16S and pre-23S rRNA processing stems and corresponding hairpin substrates, overview |
Aquifex aeolicus |
? |
- |
? |
| 3.1.26.3 | double-stranded RNA + H2O |
- |
Aquifex aeolicus |
5'-phosphooligonucleotides |
- |
? |
| 3.1.26.3 | double-stranded RNA + H2O |
responsible for processing of dsRNA |
Aquifex aeolicus |
5'-phosphooligonucleotides |
- |
? |
| 3.1.26.3 | double-stranded RNA + H2O |
RNA 5, a 30 base stem-loop RNA of the sequence 5 '-AUAAAGGUCAUUCGCAAGAGUGGCCUUUAU-3', is cleaved by RNase III (D44N) from Aquifex aeolicus. The products of the reaction include a dinucleotide 5'-AU-3' and a 28 base stem-loop RNA with a two-base 3' overhang (RNA 6). Two RNA 6 molecules and a dimeric mutant enzyme D44N molecule form a product complex |
Aquifex aeolicus |
? |
- |
? |
| 3.1.26.3 | dsRNA + H2O |
reshaping of fully or partially double-stranded RNA precursors in to mature RNAs involved in pre-mRNA splicing, RNA modification, translation, gene silencing, and regulation of developmental timing |
Aquifex aeolicus |
mature RNA |
- |
? |
| 3.1.26.3 | dsRNA + H2O |
cleavage of fully or partially double-stranded RNA precursors into mature structural and catalytic RNAs such as the snRNAs that splice pre-mRNA, rRNAs, and tRNAs that function in translation, swnoRNAs that guide modification of rRNAs, and individual mRNAs, whose expression they regulate |
Aquifex aeolicus |
mature RNA |
staggered breaks with 2 nt, 3'-overhanging ends and 5'-phosphate and 3'-hydroxy termini |
? |
| 3.1.26.3 | more |
cleave internally 32P-labeled R1.1(WC) RNA |
Aquifex aeolicus |
? |
- |
? |
| 3.1.26.3 | more |
small hairpins based on the stem structures associated with the Aquifex 16S and 23S rRNA precursors are cleaved at sites that are consistent with production of the immediate precursors to the mature rRNAs. Substrate reactivity is independent of the distal box sequence, but is strongly dependent on the proximal box sequence. RNase III mechanism of dsRNA cleavage, overview |
Aquifex aeolicus |
? |
- |
? |
| 3.1.26.3 | more |
processing of dsRNA |
Aquifex aeolicus |
? |
- |
? |
| 3.1.26.3 | double-stranded RNA + H2O |
responsible for processing and maturation of RNA precursors into functional rRNA, mRNA and other small RNA |
Arabidopsis thaliana |
5'-phosphooligonucleotides |
- |
? |
