EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.7.86 | ATP + GTP |
- |
Homo sapiens |
2 diphosphate + cyclic 3',5'-AMP-GMP |
- |
? |
2.7.7.86 | ATP + GTP |
- |
Mus musculus |
2 diphosphate + cyclic 3',5'-AMP-GMP |
- |
? |
2.7.7.86 | ATP + GTP |
- |
Homo sapiens |
2 diphosphate + cyclic Gp(2'-5')Ap(3'-5') |
- |
? |
2.7.7.86 | ATP + GTP |
- |
Homo sapiens |
2 diphosphate + cyclic Gp(2'-5')Ap(3'-5') |
product is cyclic Gp(2'-5')Ap(3'-5') |
? |
2.7.7.86 | ATP + GTP |
- |
Mus musculus |
2 diphosphate + cyclic Gp(2'-5')Ap(3'-5') |
product is cyclic Gp(2'-5')Ap(3'-5') |
? |
2.7.7.86 | more |
a diphosphatase-coupled cGAS activity assay is performed |
Homo sapiens |
? |
- |
- |
2.7.7.86 | ATP + GTP |
cyclic 3',5'-AMP-GMP is a signalling molecule in mammalian cells that triggers the production of type I interferons and other cytokines |
Homo sapiens |
2 diphosphate + cyclic 3',5'-AMP-GMP |
- |
? |
2.7.7.86 | ATP + GTP |
cyclic 3',5'-AMP-GMP is a signalling molecule in mammalian cells that triggers the production of type I interferons and other cytokines |
Mus musculus |
2 diphosphate + cyclic 3',5'-AMP-GMP |
- |
? |
2.7.7.86 | more |
interaction of cGAS and viral DNA sensor IFI16, the pyrin domain of IFI16 mediates the interaction with ND10 bodies and enzyme cGAS |
Homo sapiens |
? |
- |
- |
2.7.7.86 | ATP + GTP |
over 78% conversion within 40 min |
Mus musculus |
2 diphosphate + cyclic Gp(2'-5')Ap(3'-5') |
- |
? |