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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 1,2-bis-(O-geranylgeranyl)-sn-glycerol 3-phosphate 94% of the activity with 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate Methanothermobacter thermautotrophicus diphosphate + CDP-1,2-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 1,2-bis-(O-geranylgeranyl)-sn-glycerol 3-phosphate 94% of the activity with 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate Methanothermobacter thermautotrophicus DSM 1053 diphosphate + CDP-1,2-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate - Methanothermobacter thermautotrophicus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate - Archaeoglobus fulgidus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate - Aeropyrum pernix diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate the enzyme is involved in the biosynthesis of polar lipids in archaea Methanothermobacter thermautotrophicus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate the enzyme catalyses one of the steps in the biosynthesis of polar lipids in archaea, which are characterized by having an sn-glycerol 1-phosphate backbone rather than an sn-glycerol 3-phosphate backbone as is found in bacteria and eukaryotes Methanothermobacter thermautotrophicus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate unsaturation of the hydrocarbon chains of the substrate is critical. Archaetidic acid with saturated (2,3-phytanyl-glycerophosphate ether) or monounsaturated (2,3-phytyl-glycerophosphate ether) isoprenoid chains of the same carbon number are poor substrates as are analogs with monounsaturated straight chains (2,3-oleyl-glycerophosphate ether), even though they had the same stereostructure as the fully active natural substrate. As to the ester analogs of the substrate, the glycerophosphate esters with geranylgeranioyl chains show high activities. In this case, the 1,2-geranylgeranyl analog shows a half-maximal activity. The activities to the ester analogs of the substrate with oleoyl chains are also in low levels. The results suggest that the enzyme does not recognize ether or ester bonds between glycerophosphate and hydrocarbon chains nor the stereostructure of the glycerophosphate backbone but mainly targets substrates with geranylgeranyl chains Methanothermobacter thermautotrophicus diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate ApCarS is a CTP transferase Aeropyrum pernix diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
Show all pathways known for 2.7.7.67Display the reaction diagram Show all sequences 2.7.7.67CTP + 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate - Aeropyrum pernix ATCC 700893 diphosphate + CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol - ?
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