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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.3603 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 overall reaction Mus musculus 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.3603 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 overall reaction Xenopus tropicalis 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.3603 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 overall reaction Homo sapiens 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.3603 S-adenosyl-L-methionine + a [histone H3]-L-lysine79 overall reaction Saccharomyces cerevisiae 3 S-adenosyl-L-homocysteine + a [histone H3]-N6,N6,N6-trimethyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360more mDot1a directly or indirectly associates with and hypermethylated histone H3 K79 at specific portions of the ENaCalpha 5'-flanking region, inducing a local alteration of the chromatin structure that facilitates ENaCalpha mRNA expression Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360more AF10 bound to the enzyme simultaneously senses unmodified histone H3 lysine 27 via its PHD finger-Zn knuckle-PHD finger domain and enables the enzyme to methylate histone H3 at lysine 79. Knockout embryos, lacking Af10, have reduced [histone H3]-N6-methyl-L-lysine79 in developing nasal processes and reduced expression of AP2alpha, a gene required for cranial neural crest cell development Mus musculus ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-L-lysine79 - Mus musculus S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-L-lysine79 - Xenopus tropicalis S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-L-lysine79 - Homo sapiens S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine79 - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360S-adenosyl-L-methionine + a [histone H3]-L-lysine79 - Saccharomyces cerevisiae S-adenosyl-L-homocysteine + a [histone H3]-N6-methyl-L-lysine79 - ?
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