EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.11.8 | more |
enzyme is localized to the mitochondrial matrix, product formation is limited by 6-N-trimethyllysine transport across the mitochondrial inner membrane |
Rattus norvegicus |
? |
- |
? |
1.14.11.8 | more |
determination of the (2S,3S)-3-hydroxy-N6,N6,N6-trimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine is performed by ultraperformance liquid chromatographytandem mass spectrometry (UPLC/MS/MS) in positive ion electrospray mode |
Homo sapiens |
? |
- |
? |
1.14.11.8 | more |
NMR spectrosopic structure analysis of substrates and products |
Homo sapiens |
? |
- |
? |
1.14.11.8 | more |
NMR spectrosopic structure analysis of substrates and products, substrate specificity, overview. No or poor activity with dimethyllysine, methyllysine, lysine, D-trimethyllysine, 5-trimethylamino-1-aminopentane, trimethyllysine, 6-trimethylaminohexanoic acid, hexamethyllysine, N-acetyltrimethyllysine, trimethyldiaminobutyric acid, triethyllysine, symmetric and asymmetric dimethylarginines, mildronate, and gamma-butyrobetaine, structure-activity relationship study |
Homo sapiens |
? |
- |
? |
1.14.11.8 | N5,N5,N5-trimethyl-L-ornithine + 2-oxoglutarate + O2 |
- |
Homo sapiens |
(3S)-3-hydroxy-N5,N5,N5-trimethyl-L-ornithine + succinate + CO2 |
- |
? |
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 |
- |
Mus musculus |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 |
- |
? |
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 |
- |
Homo sapiens |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 |
- |
? |
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 |
- |
Rattus norvegicus |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 |
- |
? |
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 |
- |
Sus scrofa |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 |
- |
? |
1.14.11.8 | N6,N6,N6-trimethyl-L-lysine + 2-oxoglutarate + O2 |
- |
Neurospora crassa |
3-hydroxy-N6,N6,N6-trimethyl-L-lysine + succinate + CO2 |
- |
? |