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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
1.1.1.30
acetoacetate + NADH + H+
-
Alcaligenes faecalis
(R)-3-hydroxybutanoate + NAD+
-
?
1.1.1.30
2-methyl-3-hydroxybutyrate + NAD+
-
Paucimonas lemoignei
2-methylacetoacetate + NADH
-
r
1.1.1.30
3-hydroxyvalerate + NAD+
-
Paracoccus denitrificans
3-oxovalerate + NADH + H+
-
?
1.1.1.30
3-hydroxyvalerate + NAD+
-
Paracoccus denitrificans ATCC 17741
3-oxovalerate + NADH + H+
-
?
1.1.1.30
levulinic acid + NADH + H+
only the recombinant wild type enzyme with N-terminal His-tag shows activity with levulinic acid
Alcaligenes faecalis
4-hydroxyvaleric acid + NAD+
-
?
1.1.1.30
levulinic acid + NADH + H+
the wild type enzyme shows low activity with levulinic acid, while it's a good substrate for mutant enzyme H144L/W187F
Alcaligenes faecalis
4-hydroxyvaleric acid + NAD+
-
?
1.1.1.30
L-threonine + NAD+
-
Pseudomonas fragi
?
-
?
1.1.1.30
more
enzyme activity is differently regulated in liver and brain at euthermic, prehibernating,and hibernating state
Jaculus orientalis
?
-
?
1.1.1.30
more
a ketone body converting enzyme in mitochondria in liver jerboa, enzyme expression, activity and metabolism at different physiological states, overview
Jaculus orientalis
?
-
?
1.1.1.30
more
no activity of the wild-type enzyme with levulinic acid, enzyme mutant H144L/W187F is active with levulinic acid producing 4-hydroxyvaleric acid
Alcaligenes faecalis
?
-
?
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