EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
   2.1.1.56 | more |
the enzyme is responsible for guanine-N7 methylation of recapped mRNAs |
Homo sapiens |
? |
- |
- |
| 2.1.1.56 | more |
no activity with 7mGpppA |
Homo sapiens |
? |
- |
- |
| 2.1.1.56 | more |
no activity with 7mGpppA |
Severe acute respiratory syndrome-related coronavirus |
? |
- |
- |
| 2.1.1.56 | more |
the protein reveals cap-independent methyltransferase activities targeting internal adenosine residues. Besides this, the enzyme domain also methylates the N7 position of the cap guanosine. The enzyme preferentially methylates adenosine residues and is not active on poly G, C and U RNAs |
Sudan ebolavirus |
? |
- |
- |
| 2.1.1.56 | more |
ATP, XTP, CTP, UTP, and guanosine containing compounds with phospho groups in either position 2' or 3' or in 3'-5'phosphodiester linkage |
Vaccinia virus |
? |
- |
? |
| 2.1.1.56 | more |
isolated methyltransferase domain shows a lower but kinetically equivalent activity than the complete enzyme, which is highly enhanced by association with the D12 subunit |
Vaccinia virus |
? |
- |
? |
| 2.1.1.56 | more |
no substrates are poly-(A) terminating in a single phosphate or a diphosphate |
Homo sapiens |
? |
- |
? |
| 2.1.1.56 | more |
no substrates are poly-(A) terminating in a single phosphate or a diphosphate |
Vaccinia virus |
? |
- |
? |
| 2.1.1.56 | more |
no methylation of internal or conventional 5'-terminal guanosine residues |
Vaccinia virus |
? |
- |
? |
| 2.1.1.56 | more |
GDP, GTP, G(5')ppppG |
Homo sapiens |
? |
- |
? |
