EC Number   |
Substrates |
Organism |
Products  |
Reversibility |
|---|
    1.1.1.81 | acetoin + NAD(P)H + H+ |
33 mM, 14% of activity with hydroxypyruvate |
Paracoccus denitrificans |
2,3-butanediol + NAD(P)+ |
- |
? |
| 1.1.1.81 | 4-hydroxyphenylpyruvate + NADPH + H+ |
- |
Arabidopsis thaliana |
3-(4-hydroxyphenyl)lactate + NADP+ |
- |
? |
| 1.1.1.81 | 4-hydroxyphenylpyruvate + NADPH + H+ |
reaction of EC 1.1.1.237 |
Arabidopsis thaliana |
3-(4-hydroxyphenyl)lactate + NADP+ |
- |
? |
| 1.1.1.81 | D-glycerate + NAD+ |
- |
Bos taurus |
3-hydroxypyruvate + NADH + H+ |
- |
r |
| 1.1.1.81 | D-glycerate + NAD+ |
- |
Methylorubrum extorquens AM1 |
3-hydroxypyruvate + NADH + H+ |
- |
r |
| 1.1.1.81 | DL-glycerate + NAD+ |
- |
Bos taurus |
3-hydroxypyruvate + NADH + H+ |
- |
r |
| 1.1.1.81 | more |
enzyme deficiency leads to primary hyperoxaluria type 2 with increased urinary oxalate levels, formation of kidney stones, and renal failure |
Homo sapiens |
? |
- |
? |
| 1.1.1.81 | more |
the enzyme is transcriptionally regulated by the peroxisome proliferator-activated receptor alpha, PPARalpha, in liver, overview |
Mus musculus |
? |
- |
? |
| 1.1.1.81 | more |
structural basis of enzyme substrate specificity, active site structure and substrate binding, no activity with pyruvate, overview |
Homo sapiens |
? |
- |
? |
| 1.1.1.81 | more |
the enzyme GLYR1 has negligible hydroxypyruvate dependent activity with NADPH |
Arabidopsis thaliana |
? |
- |
? |
