    6.2.1.2 | more |
the enzyme also belongs to EC 6.2.1.30, substrate specificity, the more substituted compounds ferulic acid, caffeic acid and sinapic acid, which are substrates for most 4-coumarate CoA ligases, are very poor substrates for the enzyme. With the exception of acetic acid, all short and medium chain fatty acids tested are converted by the enzyme, the enzyme is able to activate all the side chains of these naturally occurring lactam side products, overview. Residues H265, I266, Y267, V270, F307, F335, G337, A338, G361, T369, V370, and K557 are involved in substrate binding |
Penicillium chrysogenum |
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