EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    5.4.99.2 | more |
this enzyme is deficient in methylmalonic acidemia |
Homo sapiens |
? |
- |
? |
| 5.4.99.2 | more |
acts as a cobalamin binding protein |
Oryctolagus cuniculus |
? |
- |
? |
| 5.4.99.2 | more |
P-loop GTPase MeaB plays an auxiliary role in catalytic reaction. MeaB increases affinity of the mutase for cofactor 5-deoxyadenosylcobalamin twofold |
Methylorubrum extorquens |
? |
- |
? |
| 5.4.99.2 | more |
human MMAA and MUT interact in vitro and in vivo. This interaction is nucleotide-selective for MMAA and apoenzyme-dependent for MUT and is associated with stimulation of MMAA GTPase activity by MUT |
Homo sapiens |
? |
- |
? |
| 5.4.99.2 | more |
establishment of a method to measure the concentration of succinyl-CoA with UPLC-MS/MS after enzyme reaction using peripheral lymphocytes, and investigation of the MCM activity of patients with methylmalonic acidemia, overview. usage of peripheral lymphocytes and withmethylmalonyl-CoA and adenosylcobalamin for the reaction, and analysis of acyl-CoAs by UPLC-MS/MS, structure and cleavage of succinyl-CoA and methylmalonyl-CoA in collision-induced dissociation after lymphocyte disruption. The cone voltage is 45 V and the collision energy is 30 eV |
Homo sapiens |
? |
- |
? |
| 5.4.99.2 | Succinyl-carba(dethia)-CoA |
- |
Propionibacterium freudenreichii subsp. shermanii |
? |
- |
? |
| 5.4.99.2 | Succinyl-CoA |
succinyl-CoA is isomerized to methylmalonyl-CoA before incorporation into the macrocyclic lactone of erythromycin |
Saccharopolyspora erythraea |
? |
- |
? |
| 5.4.99.2 | Succinyl-CoA |
production of propionate from succinate |
Propionibacterium freudenreichii subsp. shermanii |
? |
- |
? |
| 5.4.99.2 | Succinyl-dicarba(dethia)-CoA |
- |
Propionibacterium freudenreichii subsp. shermanii |
? |
- |
? |
