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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutyrate - Halalkalibacterium halodurans TCJAR021 2-methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutyrate - Halalkalibacterium halodurans L-ectoine + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutyrate - Halalkalibacterium halodurans TCJAR021 L-ectoine + H2O - ?
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutanoate an intramolecular condensation reaction Halomonas elongata L-ectoine + H2O - r
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutanoate an intramolecular condensation reaction Halomonas elongata L-ectoine + H2O i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid, over 95% conversion by the recombinant ectoine synthase r
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutanoate an intramolecular condensation reaction Halomonas elongata DSM 2581 L-ectoine + H2O - r
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108N4-acetyl-L-2,4-diaminobutanoate an intramolecular condensation reaction Halomonas elongata DSM 2581 L-ectoine + H2O i.e. 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid, over 95% conversion by the recombinant ectoine synthase r
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108more EctC not only effectively converts its natural substrate N-gamma-acetyl-L-2,4-diaminobutyric acid into ectoine through a cyclocondensation reaction, but it can also use the isomer N-alpha-acetyl-L-2,4-diaminobutyric acid as its substrate, albeit with substantially reduced catalytic efficiency Sphingopyxis alaskensis ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108more EctC not only effectively converts its natural substrate N-gamma-acetyl-L-2,4-diaminobutyric acid into ectoine through a cyclocondensation reaction, but it can also use the isomer N-alpha-acetyl-L-2,4-diaminobutyric acid as its substrate, albeit with substantially reduced catalytic efficiency Sphingopyxis alaskensis DSM 13593 / LMG 18877 / RB2256 ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.108more ectoine synthase accepts more than one substrate and is a reversible enzyme able to catalyze both the intramolecular condensation into and the hydrolytic cleavage of cyclic amino acid derivatives. It forms 5-amino-3,4-dihydro-2H-pyrrole-2-carboxylate, ADPC, by cyclic condensation of glutamine in a reversible reaction. A number of ectoine derivatives, in particular 4,5-dihydro-2-methylimidazole-4-carboxylate and L-homoectoine, are also cleaved by ectoine synthase. Proposed reaction mechanism leading to L-ectoine and 5-amino-3,4-dihydro-2H-pyrrole-2-carboxylate, respectively, catalyzed by ectoine synthase, overview Halomonas elongata ? - ?
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