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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.1.1.55
acetyl salicylate + H2O
active in detoxification
Rattus norvegicus
salicylate + acetate
-
?
3.1.1.55
acetyl salicylate + H2O
the rate of aspirin hydrolysis is not determined by aspirin esterase alone, other factors are probably involved
Homo sapiens
salicylate + acetate
-
?
3.1.1.55
acetyl salicylate + H2O
fatty acid-free human albumin and human plasma are treated with aspirin for 5 min-24 h. Acetylated residues are identified by LC/MS/MS and MALDI-TOF/TOF mass spectrometry of tryptic peptides. Treatment with 0.3 mM aspirin results in acetylation of Lys-199, Lys-402, Lys-519, and Lys-545. Treatment with 20 mM aspirin results in acetylation of 26 lysines. There is no acetylation of Tyr-411, under any conditions. Acetylated lysine is stable for at least 21 days at pH 7.4, 37°C
Homo sapiens
salicylate + acetate
-
?
3.1.1.55
acetylsalicylate + H2O
-
Homo sapiens
salicylate + acetate
-
?
3.1.1.55
acetylsalicylate + H2O
i.e. aspirin
Cavia porcellus
salicylate + acetate
-
?
3.1.1.55
acetylsalicylate + H2O
i.e. aspirin
Mus musculus
salicylate + acetate
-
?
3.1.1.55
acetylsalicylate + H2O
i.e. aspirin
Homo sapiens
salicylate + acetate
-
?
3.1.1.55
acetylsalicylate + H2O
i.e. aspirin
Rattus norvegicus
salicylate + acetate
-
?
3.1.1.55
acetylsalicylic acid + H2O
-
Homo sapiens
acetate + salicylate
-
?
3.1.1.55
acetylsalicylic acid + H2O
aspirin is hydrolyzed inside the erythrocytes, not in plasma
Homo sapiens
acetate + salicylate
-
?
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