EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.9.1.1 | L-seryl-tRNASec + selenophosphate |
- |
Moorella thermoacetica |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
- |
Leishmania donovani |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
- |
Aquifex aeolicus |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
sps2 encodes a selenoprotein, SPS2, which can serve as selenium donor for the biosynthesis of Sec, as an autoregulator of selenoprotein synthesis, Sec biosynthetic pathway in eukaryotes, overview |
Mus musculus |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
sps2 encodes a selenoprotein, SPS2, which can serve as selenium donor for the biosynthesis of Sec, as an autoregulator of selenoprotein synthesis, Sec biosynthetic pathway in eukaryotes, overview |
Homo sapiens |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
the enzyme is involved in selenocysteine incorporation into proteins in bacteria, pathway overview |
Moorella thermoacetica |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
the efficiency of tRNA binding in descending order is O-phosphoseryl-tRNA[Ser]Sec, tRNA[Ser]Sec, and seryl-tRNA[Ser]Sec, whereas seryl-tRNASer and tRNASer do not bind at all |
Mus musculus |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
the phosphate loop accommodates the gamma-phosphate moiety of O-phospho-L-seryltRNA [Ser]Sec and, after phosphate elimination, binds selenophosphate to initiate attack on the proposed aminoacrylyltRNA [Ser]Sec intermediate. Binding of phosphate triggers disorder-order transition in an active site loop |
Mus musculus |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-seryl-tRNASec + selenophosphate |
- |
Leishmania donovani Bob |
L-selenocysteinyl-tRNASec + phosphate |
- |
? |
| 2.9.1.1 | L-Seryl-tRNASec + sulfide |
active only at much higher concentrations than those of the thiophosphate |
Escherichia coli |
? |
- |
? |
