EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
- |
Lepeophtheirus salmonis |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
because the multifunctional ST0452 protein is capable of catalyzing the last two reactions (Ec 2.3.1.157 and EC 2.7.7.23 (UDP-N-acetylglucosamine diphosphorylase)) of the bacteria-type four-step biosynthesis pathway of UDP-GlcNAc from fructose 6-phosphate, the ST0452 protein plays an important role for the bacteria-type UDP-GlcNAc biosynthesis pathway in this archaeon |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the enzyme is involved in biosynthesis of UDP-N-acetyl-alpha-D-glucosamine, an activated and essential form of N-acetyl-alpha-D-glucosamine that is an important component in the polysaccharide structure of most organisms |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
r |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the enzyme also shows activity of EC 2.7.7.24, glucose-1-phosphate thymidylyltransferase |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
r |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the multifunctional enzyme also shows activity with UTP + alpha-D-glucose 1-phosphate (EC 2.7.7.9, UTP-glucose-1-phosphate uridylyltransferase), UTP + N-acetylglucosamine 1-phosphate (EC 2.7.7.24, glucose-1-phosphate thymidylyltransferase), dTTP + N-acetylglucosamine 1-phosphate (N-acetylglucosamine 1-phosphate thymidylyltransferase), dCTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate cytidylyltransferase), dGTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate guanylyltransferase), dATP + alpha-D-glucose 1-phosphate (glucose-1-phosphate adenylyltransferase). No activity with: alpha-D-glucose 1-phosphate + dATP, alpha-D-glucose 1-phosphate + dCTP, alpha-D-glucose 1-phosphate + dGTP, UTP + alpha-D-mannose1-phosphate, UTP + alpha-D-galactose 1-phosphate, UTP + alpha-D-glucosamine 1-phosphate |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the enzyme is involved in biosyntheis of UDP-N-acetylglusosamine |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the activity with N-acetyl-D-glucosamine-1-phosphate is 3.4 times higher, respectively, than the corresponding activity with alpha-D-glucose-1-phosphate |
Sulfurisphaera tokodaii |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
r |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
the enzyme is involved in the cell wall biosynthesis of Gram-negative organisms |
Escherichia coli |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
- |
Sulfurisphaera tokodaii 7 |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |
2.7.7.23 | UTP + N-acetyl-alpha-D-glucosamine 1-phosphate |
because the multifunctional ST0452 protein is capable of catalyzing the last two reactions (Ec 2.3.1.157 and EC 2.7.7.23 (UDP-N-acetylglucosamine diphosphorylase)) of the bacteria-type four-step biosynthesis pathway of UDP-GlcNAc from fructose 6-phosphate, the ST0452 protein plays an important role for the bacteria-type UDP-GlcNAc biosynthesis pathway in this archaeon |
Sulfurisphaera tokodaii 7 |
diphosphate + UDP-N-acetyl-alpha-D-glucosamine |
- |
? |