EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   2.7.1.137 | more |
enzyme plays an important role in the signaling of cell growth |
Bos taurus |
? |
- |
? |
| 2.7.1.137 | more |
receptor linked enzyme may generate a second-messenger signal |
Bos taurus |
? |
- |
? |
| 2.7.1.137 | ATP + 1-phosphatidylinositol |
- |
Caenorhabditis elegans |
ADP + phosphatidylinositol 3-phosphate |
- |
? |
| 2.7.1.137 | more |
regulating longevity and diapause |
Caenorhabditis elegans |
? |
- |
? |
| 2.7.1.137 | ATP + 1-phosphatidylinositol |
- |
Candida albicans |
ADP + phosphatidylinositol 3-phosphate |
- |
? |
| 2.7.1.137 | ATP + 1-phosphatidyl-1D-myo-inositol |
- |
Canis lupus familiaris |
ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate |
- |
? |
| 2.7.1.137 | ATP + 1-phosphatidyl-1D-myo-inositol |
catalyzed by class I and III, and probably by class II enzymes, overview. PI3K is part of the plasma membrane E-cadherin signaling complex |
Canis lupus familiaris |
ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate |
- |
? |
| 2.7.1.137 | more |
the enzyme is activated and associated to E-cadherin complexes, the assembly is mediated by docking proteins, e.g. beta-catenin, gamma-catenin, and Dlg, and involves c-SRC. Cell-cell adhesion induces c-SRC recruitment and E-cadherin complex assembly as well as activity of PI3K, regulatory and molecular mechanism, overview. PI3K, stimulated by E-cadherin adhesion, activates PKB/Akt |
Canis lupus familiaris |
? |
- |
? |
| 2.7.1.137 | ATP + 1-phosphatidylinositol |
- |
Cavia porcellus |
ADP + phosphatidylinositol 3-phosphate |
- |
? |
| 2.7.1.137 | more |
enzyme is involved in formyl peptide-induced stimulation of neutrophils |
Cavia porcellus |
? |
- |
? |
