EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    2.4.2.30 | more |
the bacterial enzyme shows the ability to mediate cell death in the host and is a toxin, residues 426-428 are required for this activity |
Pseudomonas aeruginosa |
? |
- |
? |
| 2.4.2.30 | more |
the enzyme is involved in endothelial cell dysfunction |
Mus musculus |
? |
- |
? |
| 2.4.2.30 | more |
the enzyme is involved in pathogenesis of Parkinson's disease, analysis of polymorphisms, overview |
Homo sapiens |
? |
- |
? |
| 2.4.2.30 | more |
transcriptional regulation mechanism, overview |
Drosophila melanogaster |
? |
- |
? |
| 2.4.2.30 | more |
transcriptional regulation mechanism, overview |
Mus musculus |
? |
- |
? |
| 2.4.2.30 | more |
exoenzyme S is a bifunctional type III secretion, TTS, effector protein, with GTPase-activating and ADP-ribosyltransferase activities |
Pseudomonas aeruginosa |
? |
- |
? |
| 2.4.2.30 | more |
ExoS is a bifunctional toxin with an N-terminal Rho GTPase activating protein, GAP, domain, and a C-terminal ADP-ribosyltransferase domain which transfers ADP-ribose from NAD onto substrates such as the Ras GTPases and vimentin |
Pseudomonas aeruginosa |
? |
- |
? |
| 2.4.2.30 | more |
ExoT is a bifunctional type III secretion system effector protein that contains an N-terminal GTPase-activating protein domain and a C-terminal ADP-ribosyl transferase domain |
Pseudomonas aeruginosa |
? |
- |
? |
| 2.4.2.30 | more |
PARP-1 protein has an N-terminal DNA binding domain containing two large zinc fingers that bind to both DNA single-strand breaks and DNA double-strand breaks, DNA binding by PARP-1 triggers its activity and it adds poly(ADP-ribose) polymers to itself and to surrounding histones, overview |
Mus musculus |
? |
- |
? |
| 2.4.2.30 | more |
the enzyme also shows NAD+-hydrolase activity |
Hathewaya limosa |
? |
- |
? |
