EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.8.4.11 | sulindac + thioredoxin |
highest activity by enzyme MsrA, low activity by enzyme MsrA1 |
Escherichia coli |
sulindac sulfide + thioredoxin disulfide + H2O |
- |
? |
1.8.4.11 | sulindac + thioredoxin |
activation of a methionine sulfoxide-containing prodrug, activity with membrane-bound enzyme form Mem-R,S-Msr |
Bos taurus |
sulindac sulfide + thioredoxin disulfide |
activated drug which inhibits cyclooxygenase 1 and 2 and exhibiting anti-inflammatory activity |
? |
1.8.4.11 | sulindac + thioredoxin |
activation of a methionine sulfoxide-containing prodrug, activity with membrane-bound enzyme form Mem-R,S-Msr and MsrA |
Escherichia coli |
sulindac sulfide + thioredoxin disulfide |
activated drug which inhibits cyclooxygenase 1 and 2 and exhibiting anti-inflammatory activity |
? |
1.8.4.11 | sulindac + thioredoxin |
activity with membrane-bound enzyme form Mem-R,S-Msr and MsrA |
Escherichia coli |
sulindac sulfide + thioredoxin disulfide |
- |
? |
1.8.4.11 | sulindac + thioredoxin |
activity with membrane-bound enzyme form Mem-R,S-Msr and MsrA |
Bos taurus |
sulindac sulfide + thioredoxin disulfide |
- |
? |
1.8.4.11 | Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + DTT |
oxidized Met-enkephalin |
Escherichia coli |
Tyr-Gly-Gly-Phe-L-methionine + DTT disulfide + H2O |
- |
? |
1.8.4.11 | Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + DTT |
oxidized Met-enkephalin |
Escherichia coli Z19 |
Tyr-Gly-Gly-Phe-L-methionine + DTT disulfide + H2O |
- |
? |
1.8.4.11 | Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + thioredoxin |
oxidized Met-enkephalin |
Escherichia coli |
Tyr-Gly-Gly-Phe-L-methionine + thioredoxin disulfide + H2O |
- |
? |
1.8.4.11 | Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + thioredoxin |
oxidized Met-enkephalin |
Escherichia coli Z19 |
Tyr-Gly-Gly-Phe-L-methionine + thioredoxin disulfide + H2O |
- |
? |