EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.17.98.4 | formate + oxidized coenzyme F420 |
- |
Methanococcus vannielii DSM 1224 |
CO2 + reduced coenzyme F420 |
- |
? |
| 1.17.98.4 | formate + [NiFe]-hydrogenase 3 |
- |
Escherichia coli |
CO2 + a [reduced hydrogenase] |
- |
? |
| 1.17.98.4 | formate + [NiFe]-hydrogenase 3 |
- |
Escherichia coli |
CO2 + reduced [NiFe]-hydrogenase 3 |
- |
? |
| 1.17.98.4 | more |
Escherichia coli possesses two hydrogenases, Hyd-3 and Hyd-4. These, in conjunction with formate dehydrogenase H (Fdh-H), constitute distinct membrane-associated formate hydrogenlyases, FHL-1 and FHL-2, both catalyzing the decomposition of formate to H2 and CO2 during fermentative growth. FHL-1 is the major pathway at acidic pH. At alkaline pH formate increases an activity of Fdh-H and of Hyd-3 both but not of Hyd-4 |
Escherichia coli |
? |
- |
? |
| 1.17.98.4 | more |
hydrogenase 3 but not hydrogenase 4 is the major enzyme in hydrogen gas production by Escherichia coli formate hydrogenlyase at acidic pH and in the presence of external formate |
Escherichia coli |
? |
- |
? |
| 1.17.98.4 | more |
physiological role of FSH-O is to ensure rapid adaptation during a shift from aerobiosis to anaerobiosis |
Escherichia coli |
? |
- |
? |
| 1.17.98.4 | more |
the enzyme catalyzes carbon exchange between carbon dioxide and formate in the absence of other electron acceptors, confirming the ping-pong reaction mechanism |
Escherichia coli |
? |
- |
? |
| 1.17.98.4 | more |
no activity with NADP+ or NAD+ |
Methanococcus vannielii |
? |
- |
? |
| 1.17.98.4 | more |
no activity with NADP+ or NAD+ |
Methanococcus vannielii DSM 1224 |
? |
- |
? |
