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Information on EC 1.17.98.4 - formate dehydrogenase (hydrogenase)

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IUBMB Comments
Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer, transferring electrons to a hydrogenase. The two enzymes form the formate-hydrogen lyase complex . The enzyme contains an [4Fe-4S] cluster, a selenocysteine residue and a molybdopterin cofactor .
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The expected taxonomic range for this enzyme is: Archaea, Bacteria
Reaction Schemes
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an [oxidized hydrogenase]
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a [reduced hydrogenase]
Synonyms
formate hydrogenlyase, formate dehydrogenase o, fdhf gene product, benzylviologen-linked formate dehydrogenase, methylviologen-dependent formate dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
formate + an [oxidized hydrogenase] = CO2 + a [reduced hydrogenase]
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PATHWAY SOURCE
PATHWAYS
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