EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   1.14.99.38 | cholesterol + AH2 + O2 |
- |
Rattus norvegicus |
25-hydroxycholesterol + A + H2O |
- |
? |
| 1.14.99.38 | cholesterol + AH2 + O2 |
testicular macrophagers play an important role in the differentiation of Leydig cells through the secretion of 25-hydroxycholesterol |
Rattus norvegicus |
25-hydroxycholesterol + A + H2O |
- |
? |
| 1.14.99.38 | cholesterol + AH2 + O2 |
expression of 25-hydroxylase mRNA and production of 25-hydroxycholesterol by cultured testicular macrophages is significantly inhibited by testosterone at 0.01 mg/ml |
Rattus norvegicus |
25-hydroxycholesterol + A + H2O |
- |
? |
| 1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Rattus norvegicus |
? |
- |
? |
| 1.14.99.38 | cholesterol + AH2 + O2 |
- |
Sus scrofa |
25-hydroxycholesterol + A + H2O |
- |
? |
| 1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Sus scrofa |
? |
- |
? |
| 1.14.99.38 | cholesterol + AH2 + O2 |
- |
Xenopus tropicalis |
25-hydroxycholesterol + A + H2O |
- |
? |
