EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    1.14.11.32 | more |
no activity with (S)-reticuline, papaverine, (S)-corytuberine, pavine, salutaridine, oripavine, noscapine |
Papaver somniferum |
? |
- |
? |
| 1.14.11.32 | neopine + 2-oxoglutarate + O2 |
- |
Papaver somniferum |
neomorphine + formaldehyde + succinate + CO2 |
- |
? |
| 1.14.11.32 | O-demethylcryptopine + 2-oxoglutarate + O2 |
a protopine, O-demethylation, 40.8% of activity with protopine |
Papaver somniferum |
? |
- |
? |
| 1.14.11.32 | protopine + 2-oxoglutarate + O2 |
best substrate |
Papaver somniferum |
? |
- |
? |
| 1.14.11.32 | scoulerine + 2-oxoglutarate + O2 |
120% of the activity with codeine |
Papaver somniferum |
3-O-demethylscoulerine + formaldehyde + succinate + CO2 |
- |
? |
| 1.14.11.32 | thebaine + 2-oxoglutarate + O2 |
- |
Papaver somniferum |
oripavine + formaldehyde + succinate + CO2 |
- |
? |
| 1.14.11.32 | thebaine + 2-oxoglutarate + O2 |
- |
Papaver orientale |
oripavine + formaldehyde + succinate + CO2 |
- |
? |
| 1.14.11.32 | thebaine + 2-oxoglutarate + O2 |
25% of the activity with codeine. Alkyl hydroxylation proceeds through a radical mechanism involving an iron-oxo intermediate, followed by the elimination of formaldehyde |
Papaver somniferum |
oripavine + formaldehyde + succinate + CO2 |
- |
? |
| 1.14.11.32 | thebaine + 2-oxoglutarate + O2 |
a morphinan, O-demethylation, 80.5% of activity with protopine |
Papaver somniferum |
? |
- |
? |
