EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.1.1.315 | all-trans-retinol + NADP+ |
- |
Homo sapiens |
all-trans-retinal + NADPH + H+ |
- |
? |
1.1.1.315 | all-trans-retinol + NADP+ |
the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 |
Homo sapiens |
all-trans-retinal + NADPH + H+ |
- |
r |
1.1.1.315 | all-trans-retinol + NADP+ |
the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 |
Mus musculus |
all-trans-retinal + NADPH + H+ |
- |
r |
1.1.1.315 | all-trans-retinol + NADP+ |
the addition of NADP+ results in more efficient oxidation of all-trans retinol into all-trans retinal, when compared with the addition of NAD+, suggesting that RDH10 prefers NADP as the cofactor. At assay conditions (pH 5.5 and pH 7.6), and NADH or NADPH is used as the cofactor, only a low level of all-trans retinol is generated by RDH10 |
Bos taurus |
all-trans-retinal + NADPH + H+ |
- |
r |