EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
    5.4.3.8 | L-glutamate 1-semialdehyde |
- |
Escherichia coli MG1655 |
5-aminolevulinate |
- |
? |
| 5.4.3.8 | L-glutamate 1-semialdehyde |
- |
Pseudomonas aeruginosa ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1 |
5-aminolevulinate |
- |
? |
| 5.4.3.8 | more |
complex formation between glutamyl-tRNA reductase and glutamate-1-semialdehyde 2,1-aminomutase in Escherichia coli during the initial reactions of porphyrin biosynthesis suggests direct metabolic channeling between both enzymes to protect the reactive aldehyde species glutamate-1-semialdehyde |
Escherichia coli |
? |
- |
? |
| 5.4.3.8 | more |
enzyme GSAM catalyzes the transamination of GSA substrate to form 5-aminolevulinate by an unusual intramolecular exchange of amino and oxo groups via the intermediate 4,5-diaminovalerate (DAVA). The reaction starts with imine formation between pyridoxamine 5'-phosphate and the aldehyde of GSA. During the first half of the reaction pyridoxamine 5'-phosphate is converted to pyridoxal 5'-phosphate, while pyridoxamine 5'-phosphate is regenerated in the second half of the reaction upon 5-aminolevulinate formation |
Arabidopsis thaliana |
? |
- |
? |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
- |
Brassica napus |
5-aminolevulinate |
- |
r |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
- |
Synechococcus sp. |
5-aminolevulinate |
- |
r |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
involved in chlorophyll biosynthesis |
Brassica napus |
5-aminolevulinate |
- |
r |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
involved in conversion of glutamate to 5-aminolevulinate |
Synechococcus sp. |
5-aminolevulinate |
- |
r |
