EC Number   |
General Information |
Reference |
|---|
    4.2.3.124 | evolution |
2-deoxy-scyllo-inosose synthase, i.e. DOIS or BtrC, clearly belongs to the family of dehydroquinate synthase, DHQS |
719040 |
| 4.2.3.124 | evolution |
evolutionary relationship between dehydroquinate synthase and 2-deoxy-scyllo-inosose synthase, overview |
719279 |
| 4.2.3.124 | malfunction |
disruption of gene btrC2 reduces the growth rate and antibiotics production, the growth rate is restored by addition of NH4Cl, both by addition of yeast extract |
-, 719110 |
| 4.2.3.124 | metabolism |
2-deoxy-scyllo-inosose synthase is the starter enzyme for 2-deoxystreptamine biosynthesis. 2-Deoxystreptamine is the aglycon of clinically important aminocyclitol antibiotics |
-, 719108 |
| 4.2.3.124 | metabolism |
2-deoxy-scyllo-inosose synthase, DOIS, is a key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics |
-, 720081 |
| 4.2.3.124 | metabolism |
DOI synthase is a key enzyme in the biosynthesis of 2-deoxy-scyllo-inosose, DOS |
-, 720206 |
| 4.2.3.124 | metabolism |
DOI synthase is the key starter enzyme of 2-deoxystreptamine biosynthesis |
719279 |
| 4.2.3.124 | metabolism |
key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics |
719040 |
| 4.2.3.124 | metabolism |
key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics. Multistep cyclization of D-glucose-6-phosphate into the six-membered carbocycle 2-deoxy-L-scyllo-inosose is the first step of 2-deoxystreptamine biosynthesis |
-, 718486 |
| 4.2.3.124 | metabolism |
key enzyme in the biosynthesis of 2-deoxytstreptamine. The function od BtrC2 in biosynthesis of butirosin is indirect. BtrC2 is involved in secondary as well as primary metabolism probably playing a role in stabilizing and regulating DOI synthase |
-, 719110 |
