EC Number   |
General Information |
Reference |
|---|
   4.2.1.133 | evolution |
protein-based phylogenetic analysis of plant diterpene synthases, overview |
720734 |
| 4.2.1.133 | evolution |
the enzyme is a class II diterpene synthase (diTPS) of specialized labdane-type metabolism. Evolutionary potential of enzymes of this family to drive rapid diversification of plant diterpene biosynthesis through neo-functionalization. Reaction mechanisms of class II diTPSs (a), and labdane-type diterpenes, overview |
748890 |
| 4.2.1.133 | evolution |
the enzyme is a class II diterpene synthase (diTPS), expression profiling and phylogenetic analysis of the CfTPS family. Coleus forskohlii diTPSs constitute a small gene family. Schematic overview of the biosynthetic routes from GGPP to specialized and general diterpenoids of the abietane, labdane, and ent-kaurene class |
743490 |
| 4.2.1.133 | evolution |
the Solanaceae functional gene cluster evolved by duplication and divergence of TPS genes, together with alterations in substrate specificity to utilize cis-prenyl diphosphates and through the acquisition of CPT genes |
730604 |
| 4.2.1.133 | metabolism |
copal-8-ol diphosphate, which is made from the all-trans geranylgeranyl diphosphate by copal-8-ol diphosphate synthase Nt-CPS2, is the substrate for Z-abienol synthase |
730604 |
| 4.2.1.133 | metabolism |
enzyme CfTPS2 synthesizes the intermediate copal-8-ol diphosphate,which in combination with CfTPS3 results in the stereospecific formation of (13R) manoyl oxide, while the combination of CfTPS1 an CfTPS3 or CfTPS4 leads to formation of miltiradiene, precursor of abietane diterpenoids in Coleus forskohlii, in combination with TPS14, (13R) and (13S) manoyl oxides are fomed |
743490 |
| 4.2.1.133 | metabolism |
the enzyme is a class II diterpene synthase (diTPS) of specialized labdane-type metabolism |
748890 |
| 4.2.1.133 | more |
analysis of diterpenoids in oil bodies from Coleus forskohlii, overview |
743490 |
| 4.2.1.133 | more |
enzyme structure homology modelling based on an the crystal structure of the Arabidopsis thaliana ent-copalyl diphosphate synthase, EC 5.5.1.13, active structure analysis, structure-function relationship analysis, overview |
748890 |
| 4.2.1.133 | physiological function |
enzyme TwTPS21 catalyzes bicyclization of the linear C20 precursor geranylgeranyl diphosphate to ent-copal-8-ol diphosphate |
748890 |
