EC Number   |
General Information |
Reference  |
|---|
   3.4.24.85 | physiological function |
HurP is essential for heme-dependent induction of bhuR and downstream genes |
710497 |
| 3.4.24.85 | physiological function |
the enzyme is involved in activation of the crucial membrane-associated transcription factors deltaK during sporulation |
710497 |
| 3.4.24.85 | physiological function |
the enzyme is involved in the feedback regulation of sterol and fatty acid synthesis and uptake by controlling the activity of transcription factors, sterol regulatory element binding proteins. Through the S2P cascade, the cholesterol feedback pathway in humans is stringently regulated |
710497 |
| 3.4.24.85 | physiological function |
the enzyme is involved in the production of pheromone cAD1, cPD1, and cCF10, and inhibitor peptide iAD1 and iCF10.The enzyme processes the sex pheromone and inhibitor precursors as they pass through the cell membrane |
710497 |
| 3.4.24.85 | physiological function |
RasP is involved in transmembrane stress signal transduction |
720919 |
| 3.4.24.85 | physiological function |
RseP introduces a cleavage into signal peptides after their signal peptidase-mediated liberation from preproteins. The enzyme is involved in degradation of remnant signal peptides left in the bacterial cytoplasmic membrane |
720919 |
| 3.4.24.85 | physiological function |
knock-out of sll0528 gene increases Synechocystis sp. PCC 6803 sensitivity to salt, cold and hyperosmotic stress, as revealed by retarded growth, reduced pigments and disrupted photosystems |
734002 |
| 3.4.24.85 | physiological function |
gene product is essential for growth. A partially segregated mutant displays defective acid acclimation to pH 6.5. Early acid acclimation to pH 6.5 in the wild-type strain includes upregulation of sigH, hik16 and hik35 and downregulation of pcrR and sigG, as well as downregulation of porins and upregulation of inorganic carbon and nitrogen transporters. The inability of the mutant strain to survive at pH 6.5 is related to defective photosynthesis and excess expression of NADH dehydrogenase, together with excessive upregulation of carbon transporter and repression of nitrogen transporter and metabolism genes. Slr0643 disruption and expression of the sigH operon are closely related |
734641 |
| 3.4.24.85 | physiological function |
loss-of-function mutant confers high sensitivity to abscisic acid during seed germination. Site-2 protease desensitizes abscisic acid signaling during seed germination through regulating the activation of the membrane-associated transcription factor bZIP17 and therefore controlling the expression level of genes encoding negative regulators of abscisic acid signaling |
734789 |
| 3.4.24.85 | physiological function |
cells defective in the site-2 protease gene have remarkably higher level of superoxide and elevated rates of cell death than wild-type CHO cells. Lack of the site-2 proease gene leads to cells more vulnerable to oxidative stress. Compared with wild-type CHO cells, mutant cells have higher nicotinamide adenine dinucleotide phosphate oxidase activity and lower paraoxonase-2 expression |
735261 |
