EC Number   |
General Information |
Reference |
|---|
    3.1.1.1 | evolution |
CaesCCR11 as a member of family XV of lipolytic enzymes, it has a canonical alpha/beta hydrolase fold composed of 7 beta-strands and 6 alpha-helices, the alpha/beta architecture of the cap domain, the GLSTG pentapeptide, and the formation of distinctive salt bridges |
-, 751539 |
| 3.1.1.1 | evolution |
carboxylesterases (CES) are a subset of esterases that belong to the alpha/beta hydrolase family |
749792 |
| 3.1.1.1 | evolution |
carboxylesterases are members of the alpha/beta hydrolase family, found in animals, plants, and microorganisms. EstPS1 has a single catalytic domain of the alpha/beta hydrolase family and belongs to the carboxylesterase family. And the EstPS1 carboxylesterase is an intracellular serine hydrolase that belongs to the lipase GDSL-2 family. Members of the GDSL family possess the GDSX motif (equivalent to the classical GXSXG motif of lipases/esterases), in which nucleophilic Ser is located in block I of the protein |
-, 752220 |
| 3.1.1.1 | evolution |
CES belongs to the serine hydrolase family |
-, 750612 |
| 3.1.1.1 | evolution |
phylogenetic analysis, BdB1 is classified into carboxylesterases clade B |
750358 |
| 3.1.1.1 | evolution |
porcine liver carboxylesterase (PLE), with the consensus sequence motif Gly-Glu-Ser-Ala-Gly in its lipolitic active site, belongs to carboxylesterase family as a serine-type esterase |
750445 |
| 3.1.1.1 | evolution |
the enzyme belongs to the serine protease superfamily |
751823 |
| 3.1.1.1 | evolution |
the enzyme NaM1 belongs to the carbohydrate esterase 7 (CE7) family enzymes, i.e. Axe1NaM1. CE7 enzymes are intracellular enzymes that possess a unique and narrow specificity for acetylated substrates. The putative AcXE-encoding genes, Axe1NaM1 (CE7), Axe1NaM2 (CE7), and XynBNaM3-like (CE3), have 64, 69, and 59% sequence identities, respectively, to known AcXE sequences from actinobacteria and distinct domain arrangements. The Axe1 domains are encoded by nucleotides 19 to 966 and 19 to 972 of the Axe1NaM1 and Axe1NaM2 genes, respectively, and shared 46.5% sequence identity. The two genes are located on two distinct contigs. The Axe1NaM1, Axe1NaM2, and XynBNaM3-like proteins, i.e. NaM1, NaM2, and NaM3, all exhibit a Ser-His-Asp(Glu) catalytic triad and a GXSXG or GDS(L) motif typical of the CE7 or CE3 family, respectively |
749674 |
| 3.1.1.1 | evolution |
the enzyme NaM2 belongs to the carbohydrate esterase 7 (CE7) family enzymes. CE7 enzymes are intracellular enzymes that possess a unique and narrow specificity for acetylated substrates. The putative AcXE-encoding genes, Axe1NaM1 (CE7), Axe1NaM2 (CE7), and XynBNaM3-like (CE3), have 64, 69, and 59% sequence identities, respectively, to known AcXE sequences from actinobacteria and distinct domain arrangements. The Axe1 domains are encoded by nucleotides 19 to 966 and 19 to 972 of the Axe1NaM1 and Axe1NaM2 genes, respectively, and share 46.5% sequence identity. The two genes are located on two distinct contigs. The Axe1NaM1, Axe1NaM2, and XynBNaM3-like proteins, i.e. NaM1, NaM2, and NaM3, all exhibit a Ser-His-Asp(Glu) catalytic triad and a GXSXG or GDS(L) motif typical of the CE7 or CE3 family, respectively |
749674 |
| 3.1.1.1 | evolution |
the enzyme shows typical characteristics of the CCE gene family, including the catalytic triad comprised by Ser186, Glu345 and His463 |
751800 |
