   2.8.2.38 | evolution |
sulfotransferases (SOTs or SULTs) can be found in all organisms analysed so far. In Arabidopsis thaliana, twenty-two sulfotransferase (SOT) isoforms are identified. Three of those are involved in glucosinolate (Gl) biosynthesis, glycosylated sulfur-containing aldoximes containing chemically different side chains, whose breakdown products are involved in stress response against herbivores, pathogens, and abiotic stress. The structure of AtSOT18 invigorates the similarity between plant and mammalian sulfotransferases, which illustrates the evolutionary conservation of this multifunctional enzyme family. In Arabidopsis thaliana, the three SOTs AtSOT16, AtSOT17 and AtSOT18 exclusively catalyse the transfer of a sulfuryl group to different ds-Gls. All three enzymes are localized in the cytoplasm and their expression pattern tested under several conditions is similar. They show 72% sequence identity but differ remarkably in their substrate specificity |
-, 762438 |
