EC Number |
General Information |
Reference |
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2.5.1.81 | evolution |
phylogenetic analysis suggest that GFDPS probably evolved from plant geranylgeranyl diphosphate synthase under the influence of positive selection. Lc-GFDPS clusters in subcluster Ia, which is dominated by GGDPS sequences |
739299 |
2.5.1.81 | malfunction |
plants overexpressing gene AtIDS9 display a distinct growth phenotype in which young leaves have bleached patches that are not found on leaves of wild-type or AtIDS11 overexpressing lines |
-, 739320 |
2.5.1.81 | metabolism |
biosynthesis of the C25 precursor geranylfarnesyl diphosphate to leucosceptroid sesterterpenoids is catalyzed by enzyme GFDPS that uses substrates geranylgeranyl diphosphate and Iisopentenyl diphosphate derived from the plastidial MEP pathway, overview |
739299 |
2.5.1.81 | more |
GFDP synthase activity is associated with specific amino acid residues of the first arginine-rich motif DDxxxxD |
-, 739320 |
2.5.1.81 | physiological function |
the geranylfarnesyl diphosphate synthase provides the precursor for sesterterpenoid (C25) formation in the glandular trichomes of the mint species Leucosceptrum canum, the C25 terpenoids might play a defensive role |
739299 |