EC Number |
General Information |
Reference |
---|
1.2.1.61 | metabolism |
enzyme is part of the degradation pathway of 4-nitrophenol which is a priority environmental pollutant |
-, 719179 |
1.2.1.61 | metabolism |
HqdC gene is part of a gene cluster associated with hydroquinone degradation into 3-oxoadipate |
-, 724063 |
1.2.1.61 | more |
highly conserved residues C281 and E247 are identified to be critical for its catalytic activity, and flexible docking studies of the enzyme-substrate system predict the interactions between PnpE and its substrate 4-hydroxymuconic semialdehyde, flexible docking of substrate to PnpE, molecular docking analysis, overview |
742206 |
1.2.1.61 | physiological function |
the pnpE-encoded enzyme gamma-hydroxymuconic semialdehyde dehydrogenase catalyzes the reduction of 4-hydroxymuconic semialdehyde to maleylacetate in Pseudomonas sp. strain WBC-3, playing a key role in the catabolism of toxic para-nitrophenol to Krebs cycle intermediates |
742206 |