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Information on EC 1.2.1.61 - 4-hydroxymuconic-semialdehyde dehydrogenase

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IUBMB Comments
Involved in the 4-nitrophenol degradation pathway.
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The enzyme appears in viruses and cellular organisms
Synonyms
4-HS dehydrogenase, 4-hydroxymuconic semialdehyde dehydrogenase, gamma-hydroxymuconic semialdehyde dehydrogenase, hAPE, HqdC, NAD dependent gamma-hydroxymuconic semialdehyde dehydrogenase, PdcG, pnpE, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-hydroxymuconic semialdehyde + NAD+ + H2O = maleylacetate + NADH + 2 H+
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