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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 1.1.1.341physiological function enzyme catalyzes the last step in synthesis of CDP-abequose from CPD-glucose. The 3,6-dideoxyhexose biosynthetic genes are clustered and relatively conserved throughout all four serogroups of Yersinia tuberculosis 719684
Display the reaction diagram Show all sequences 1.1.1.341physiological function enzyme is involved in synthesis of abequose, a constituent of the O-antigen of Salmonella B group strains 719679
Display the reaction diagram Show all sequences 1.1.1.341physiological function insertion of the gene rfbJ encoding abequose synthase into a suicide vector and integration into the rfb clusters of wild-type Salmonella typhi Vi-positive strain ISP 1820, Salmonella typhi Vi-negative strain H400, and a double aro mutant of Salmonella typhi ISP 1820, strain CVD 906. Strains carrying the vector express the O4 antigen in place of the O9 antigen in the lipopolysaccharide molecule. Results suggest that the development of the 0-antigen serotype diversity of Salmonella is probably the result of both sequence divergence and recombination between heterologous rfb sequences. In addition, the results support the hypothesis that the chemical composition of the Salmonella 0-antigen influences the interaction of individual serotypes with complement -, 720485
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