EC Number |
General Information |
Reference |
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2.4.1.90 | malfunction |
enzyme knockdown can inhibit astrocytes migration with and without lipopolysaccharide |
757808 |
2.4.1.90 | malfunction |
knock-down of the B4GALT1 gene and the inhibition of membrane B4GALT1 function results in the significant inhibition of estrogen-induced proliferation of MCF-7 cells |
718763 |
2.4.1.90 | malfunction |
short hairpin RNA-mediated enzyme knockdown inhibits the tumorigenesis of glioma stem-like cells and reduces their transdifferentiation into endothelial cells |
757209 |
2.4.1.90 | physiological function |
B4GALT1 plays a crucial role in the proliferation of MCF-7 cells through its activity as a membrane receptor |
718763 |
2.4.1.90 | physiological function |
enzyme overexpression increases migration, invasion, and tumor growth of neuroblastoma cells, increases lactosamine glycans on beta1-integrin, increases expression of mature beta1-integrin via delayed degradation, and enhances phosphorylation of focal adhesion kinase |
735973 |
2.4.1.90 | physiological function |
the enzyme promotes glioma cell growth. Enzyme overexpression increases glioma stem-like cell transdifferentiation into endothelial cells. The enzyme stimulates transdifferentiation of glioma stem-like cells into endothelial cells by activating Notch1 signaling |
757209 |