Protein Variants | Comment | Organism |
---|---|---|
Y268G/W294G | inactive | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-galactose + N-acetyl-D-glucosamine | Homo sapiens | - |
UDP + N-acetyllactosamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
GBM cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-alpha-D-galactose + N-acetyl-D-glucosamine | - |
Homo sapiens | UDP + N-acetyllactosamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
beta1,4-galactosyltransferase V | - |
Homo sapiens |
beta1,4GalTV | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | short hairpin RNA-mediated enzyme knockdown inhibits the tumorigenesis of glioma stem-like cells and reduces their transdifferentiation into endothelial cells | Homo sapiens |
physiological function | the enzyme promotes glioma cell growth. Enzyme overexpression increases glioma stem-like cell transdifferentiation into endothelial cells. The enzyme stimulates transdifferentiation of glioma stem-like cells into endothelial cells by activating Notch1 signaling | Homo sapiens |