EC Number   |
General Information |
Reference |
|---|
   3.4.21.B28 | physiological function |
the enzyme plays a role in mediating communication between activated fibroblasts and macrophages |
755114 |
| 3.4.21.B28 | physiological function |
the enzyme promotes cell growth, adhesion, invasion and migration in breast cancer. Its regulatory effects are independent of its enzymatic activity. The PI3K/AKT and MMP2/9 signaling pathway might be involved in the effects of FAPalpha on breast cancer cells |
753136 |
| 3.4.21.B28 | physiological function |
the enzyme promotes ovarian cancer cell proliferation, drug resistance, invasiveness, and migration in vitro and it significantly facilitates tumor growth in xenograft tumor tissues. The enzyme might directly promote tumor growth and invasiveness in ovarian cancer cells |
731043 |
| 3.4.21.B28 | physiological function |
the enzyme promotes the ability of proliferation, migration, invasion, apoptosis-inhibition of SGC7901 cells and induces apoptosis of GES1 cells in vitro |
753092 |
| 3.4.21.B28 | physiological function |
the enzyme promotes the growth and migration of lung cancer cells via the phosphatidylinositol-3-kinase and sonic hedgehog pathways |
753899 |
