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EC Number	Expression	Commentary	Reference
7.2.2.2	down	in the absence of its cadmium substrate, Pca1 is rapidly degraded through the endoplasmic reticulum-associated degradation pathway	713395
7.2.2.2	down	the expression of gene YFC1 is downregulated in presence of Cd2+, which affects the YFC1 promoter	-, 701314
7.2.2.2	more	endoplasmic reticulum-associated degradation (ERAD) system is responsible for the regulation of Pca1 expression by cadmium. Direct cadmium sensing at the endoplasmic reticulum by a degron in Pca1 leads to an escape of Pca1 from endoplasmic reticulum-associated degradation	713395

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Release 2023.1 (January 2023)