EC Number   |
Expression |
Reference |
|---|
    3.1.3.5 | down |
transgenic mice expressing a dominant active mutant of downstream regulatory element antagonist modulator, daDREAM, show a drastic reduction of the amount of transcript of Ca2+-activated nucleotidase. Ca2+-activated nucleotidase down-regulation is also found in neuroblastoma SH-SY5Y cells stably overexpressing wild type DREAM or daDREAM, thus providing a simple cell model to investigate the protein maturation pathway. The down-regulation of CANT1 is associated with reduced protein secretion and increased degradation rates |
729985 |
| 3.1.3.5 | up |
5'-nucleotidase UshA is induced when phosphate is limiting |
716355 |
| 3.1.3.5 | up |
5'-nucleotidases Sdt1 and Phm8 are induced at the transcript level by phosphate starvation |
716355 |
| 3.1.3.5 | up |
after scratch wounding, the abundance of enzyme mRNA increases more than 2fold |
750661 |
| 3.1.3.5 | up |
an infection with Fasciola hepatica leads to 68% higher enzyme activity 87 days after infection in serum and tissue |
751791 |
| 3.1.3.5 | up |
CD73 is highly induced by ischemia and hypoxia, and increased expression in cardiac ischemia is mediated by a positive feedback loop involving adenosine. Though CD73 is mainly regulated transcriptionally, cross linking of CD38, a cell surface glycoprotein with cyclic ADP-ribose hydrolase activity, causes upregulation of CD73 via export of protein to the cell surface that is independent of new transcription |
716355 |
| 3.1.3.5 | up |
enzyme expression is higher in papillary thyroid carcinoma cells than in the adjacent non-malignant thyroid tissue |
751564 |
| 3.1.3.5 | up |
enzyme is overexpressed during Xylella fastidiosa biofilm formation, particularly in the early stages of its formation |
-, 730334 |
| 3.1.3.5 | up |
expression and activity are maximal at the estrus phase |
707006 |
| 3.1.3.5 | up |
fibroblast growth factor 2 upregulates protein expression of the enzyme in spinal cord astrocytes |
751384 |
