EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
    3.5.4.9 | 756337 |
Crystal structure of the emerging cancer target MTHFD2 in complex with a substrate-based inhibitor |
Cancer Res. |
77 |
937-948 |
2017 |
Homo sapiens |
27899380 |
| 3.5.4.9 | 756334 |
Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase |
Cancer Metab. |
5 |
11 |
2017 |
Homo sapiens |
29225823 |
| 3.5.4.9 | 744335 |
Impact of mutating the key residues of a bifunctional 5,10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Escherichia coli on its activities |
Biochemistry |
54 |
3504-3513 |
2015 |
Escherichia coli |
25988590 |
| 3.5.4.9 | 744335 |
Impact of mutating the key residues of a bifunctional 5,10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Escherichia coli on its activities |
Biochemistry |
54 |
3504-3513 |
2015 |
Escherichia coli K12 |
25988590 |
| 3.5.4.9 | 757773 |
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells |
Nat. Commun. |
9 |
2292 |
2018 |
Homo sapiens |
29895827 |
| 3.5.4.9 | 743250 |
Physiological role of FolD (methylenetetrahydrofolate dehydrogenase), FchA (methenyltetrahydrofolate cyclohydrolase) and Fhs (formyltetrahydrofolate synthetase) from Clostridium perfringens in a heterologous model of Escherichia coli |
Microbiology |
162 |
145-155 |
2016 |
Clostridium perfringens |
26531681 |
| 3.5.4.9 | 209722 |
5,10-Methenyltetrahydrofolate cyclohydrolase and 5-formyltetrahydrofolate cyclodehydrase in Aedes aegypti |
Comp. Biochem. Physiol. B |
66 |
597-600 |
1980 |
Aedes aegypti |
- |
| 3.5.4.9 | 209722 |
5,10-Methenyltetrahydrofolate cyclohydrolase and 5-formyltetrahydrofolate cyclodehydrase in Aedes aegypti |
Comp. Biochem. Physiol. B |
66 |
597-600 |
1980 |
Bos taurus |
- |
| 3.5.4.9 | 209722 |
5,10-Methenyltetrahydrofolate cyclohydrolase and 5-formyltetrahydrofolate cyclodehydrase in Aedes aegypti |
Comp. Biochem. Physiol. B |
66 |
597-600 |
1980 |
Oryctolagus cuniculus |
- |
| 3.5.4.9 | 209722 |
5,10-Methenyltetrahydrofolate cyclohydrolase and 5-formyltetrahydrofolate cyclodehydrase in Aedes aegypti |
Comp. Biochem. Physiol. B |
66 |
597-600 |
1980 |
Ovis aries |
- |
