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EC Number
BRENDA No.
Title
Journal
Volume
Pages
Year
Organism
PubMed ID
3.4.24.85
752837
Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease
Biochim. Biophys. Acta Biomembr.
1859
1859-1871
2017
Archaeoglobus fulgidus
28502790
3.4.24.85
678495
De novo cholesterol synthesis at the crossroads of adaptive response to extracellular stress through SREBP
Biochimie
89
260-264
2007
Schizosaccharomyces pombe
17059860
3.4.24.85
644081
Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans
Cell
100
391-398
2000
Homo sapiens
10693756
3.4.24.85
753352
Structural biology of intramembrane proteases Mechanistic insights from rhomboid and S2P to gamma-secretase
Curr. Opin. Struct. Biol.
37
97-107
2016
Methanocaldococcus jannaschii
26811996
3.4.24.85
679400
Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases
Curr. Opin. Struct. Biol.
18
432-441
2008
Methanocaldococcus jannaschii
18440799
3.4.24.85
679505
Spatial separation of Golgi and ER during mitosis protects SREBP from unregulated activation
EMBO J.
27
948-955
2008
Rattus norvegicus
18323777
3.4.24.85
668488
Signal peptide peptidase dependent cleavage of type II transmembrane substrates releases intracellular and extracellular signals
Eur. J. Pharmacol.
540
10-17
2006
Chlorocebus aethiops
16697367
3.4.24.85
733824
Nelfinavir inhibits regulated intramembrane proteolysis of sterol regulatory element binding protein-1 and activating transcription factor 6 in castration-resistant prostate cancer
FEBS J.
279
2399-2411
2012
Homo sapiens
22540830
3.4.24.85
753581
Baicalin promoted site-2 protease and not site-1 protease in endoplasmic reticulum stress-induced apoptosis of human hepatocellular carcinoma cells
FEBS Open Bio
6
1093-1101
2016
Homo sapiens
27833850
3.4.24.85
644083
Characterization of the yaeL gene product and its S2P-protease motifs in Escherichia coli
Gene
281
71-79
2001
Escherichia coli
11750129
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