EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
    1.3.1.22 | 763398 |
11alpha-Hydroxyprogesterone, a potent 11alpha-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5alpha-reductase and cytochrome P450 17alpha-hydroxylase/17,20-lyase to produce C11alpha-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro |
J. Steroid Biochem. Mol. Biol. |
191 |
105369 |
2019 |
Homo sapiens |
31039398 |
| 1.3.1.22 | 743212 |
Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors |
Med. Chem. Res. |
26 |
1550-1556 |
2017 |
Homo sapiens |
- |
| 1.3.1.22 | 743212 |
Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors |
Med. Chem. Res. |
26 |
1550-1556 |
2017 |
Homo sapiens CRL-1740 |
- |
| 1.3.1.22 | 762009 |
Apigenin inhibits rat neurosteroidogenic 5alpha-reductase 1 and 3alpha-hydroxysteroid dehydrogenase |
Neurochem. Int. |
110 |
84-90 |
2017 |
Rattus norvegicus |
28947342 |
| 1.3.1.22 | 762014 |
Butylated hydroxyanisole alters rat 5alpha-reductase and 3alpha-hydroxysteroid dehydrogenase Implications for influences of neurosteroidogenesis |
Neurosci. Lett. |
653 |
132-138 |
2017 |
Rattus norvegicus |
28552457 |
| 1.3.1.22 | 763504 |
Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism |
Nat. Commun. |
12 |
449 |
2021 |
Proteobacteria bacterium |
33469028 |
| 1.3.1.22 | 762972 |
Expression in Escherichia Coli, purification, and functional reconstitution of human steroid 5alpha-reductases |
Endocrinology |
161 |
bqaa117 |
2020 |
Homo sapiens |
32716491 |
| 1.3.1.22 | 763501 |
Structure of human steroid 5alpha-reductase 2 with the anti-androgen drug finasteride |
Nat. Commun. |
11 |
5430 |
2020 |
Homo sapiens |
33110062 |
| 1.3.1.22 | 762902 |
Synthesis, biological evaluation and molecular docking of avicequinone C analogues as potential steroid 5alpha-reductase inhibitors |
Chem. Pharm. Bull. |
65 |
253-260 |
2017 |
Homo sapiens |
28250347 |
| 1.3.1.22 | 685587 |
3,3-diphenylpentane skeleton as a steroid skeleton substitute: novel inhibitors of human 5alpha-reductase 1 |
Bioorg. Med. Chem. Lett. |
17 |
5414-5418 |
2007 |
Homo sapiens |
17686629 |
