EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism |
PubMed ID |
|---|
   1.1.1.146 | 761361 |
11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis |
J. Autoimmun. |
92 |
104-113 |
2018 |
Mus musculus |
29891135 |
| 1.1.1.146 | 761665 |
11beta-Hydroxysteroid dehydrogenases control access of 7beta,27-dihydroxycholesterol to retinoid-related orphan receptor gamma |
J. Lipid Res. |
60 |
1535-1546 |
2019 |
Homo sapiens |
31273032 |
| 1.1.1.146 | 760680 |
A novel derivatives of thiazol-4(5H)-one and their activity in the inhibition of 11beta-hydroxysteroid dehydrogenase type 1 |
Bioorg. Chem. |
79 |
115-121 |
2018 |
Homo sapiens |
29738970 |
| 1.1.1.146 | 760802 |
Characterisation of the cancer-associated glucocorticoid system key role of 11beta-hydroxysteroid dehydrogenase type 2 |
Br. J. Cancer |
117 |
984-993 |
2017 |
Homo sapiens |
28797028 |
| 1.1.1.146 | 760685 |
Design, synthesis, and biological evaluation of novel selective peptide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
Bioorg. Med. Chem. |
26 |
5128-5139 |
2018 |
Homo sapiens |
30245006 |
| 1.1.1.146 | 761908 |
Design, synthesis, molecular docking and in vitro evaluation of benzothiazole derivatives as 11beta-hydroxysteroid dehydrogenase type 1 inhibitors |
Mol. Divers. |
24 |
971-984 |
2020 |
Rattus norvegicus |
31664610 |
| 1.1.1.146 | 760876 |
Discovery and biological evaluation of potent and orally active human 11beta-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of type 2 diabetes mellitus |
Chem. Pharm. Bull. |
67 |
824-838 |
2019 |
Homo sapiens |
31366832 |
| 1.1.1.146 | 761758 |
Enzymatic interconversion of the oxysterols 7beta,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11beta-hydroxysteroid dehydrogenase type 1 and 2 |
J. Steroid Biochem. Mol. Biol. |
190 |
19-28 |
2019 |
Homo sapiens |
30902677 |
| 1.1.1.146 | 761758 |
Enzymatic interconversion of the oxysterols 7beta,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11beta-hydroxysteroid dehydrogenase type 1 and 2 |
J. Steroid Biochem. Mol. Biol. |
190 |
19-28 |
2019 |
Mus musculus |
30902677 |
| 1.1.1.146 | 760868 |
Expression and activity of the cortisol-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 is tissue and species-specific |
Chem. Biol. Interact. |
303 |
57-61 |
2019 |
Homo sapiens |
30796905 |
