EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages  |
Year |
Organism |
PubMed ID |
|---|
   3.4.21.47 | 754745 |
The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models |
Mol. Immunol. |
105 |
150-164 |
2019 |
Homo sapiens |
30513451 |
| 3.4.21.47 | 753663 |
Functional characterization of alternative and classical pathway C3/C5 convertase activity and inhibition using purified models |
Front. Immunol. |
9 |
1691 |
2018 |
Homo sapiens |
30083158 |
| 3.4.21.47 | 752433 |
C5 convertase blockade in membranoproliferative glomerulonephritis a single-arm clinical trial |
Am. J. Kidney Dis. |
74 |
224-238 |
2019 |
Homo sapiens |
30929851 |
| 3.4.21.47 | 753082 |
Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes |
BMC Biol. |
13 |
93 |
2015 |
Homo sapiens |
26552476 |
| 3.4.21.47 | 755170 |
Neisseria heparin binding antigen is targeted by the human alternative pathway C3-convertase |
PLoS ONE |
13 |
e0194662 |
2018 |
Homo sapiens |
29579105 |
| 3.4.21.47 | 753422 |
Bacterial killing by complement requires membrane attack complex formation via surface-bound C5 convertases |
EMBO J. |
38 |
e99852 |
2019 |
Homo sapiens |
30643019 |
| 3.4.21.47 | 649815 |
Structure and function of complement C5 convertase enzymes |
Biochem. Soc. Trans. |
30 |
1006-1010 |
2002 |
Homo sapiens |
12440962 |
| 3.4.21.47 | 36597 |
Human factor B |
Methods Enzymol. |
80 |
102-112 |
1981 |
Homo sapiens |
7043188 |
| 3.4.21.47 | 709002 |
Structural and functional analysis of a C3b-specific antibody that selectively inhibits the alternative pathway of complement |
J. Biol. Chem. |
284 |
10473-10479 |
2009 |
Homo sapiens |
19196712 |
| 3.4.21.47 | 36594 |
The activation of human complement component C5 by a fluid phase C5 convertase |
J. Biol. Chem. |
258 |
10629-10636 |
1983 |
Homo sapiens |
6554279 |
