EC Number   |
BRENDA No. |
Title |
Journal |
Volume |
Pages |
Year |
Organism  |
PubMed ID |
|---|
   3.1.1.84 | 698483 |
Fundamental reaction mechanism and free energy profile for (-)-cocaine hydrolysis catalyzed by cocaine esterase |
J. Am. Chem. Soc. |
131 |
11964-11975 |
2003 |
Rhodococcus sp. |
19642701 |
| 3.1.1.84 | 695729 |
Gene cloning and nucleotide sequencing and properties of a cocaine esterase from Rhodococcus sp. strain MB1 |
Appl. Environ. Microbiol. |
66 |
904-908 |
2000 |
Rhodococcus sp. |
10698749 |
| 3.1.1.84 | 728856 |
Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification |
ACS Chem. Biol. |
9 |
1764-1772 |
2014 |
Rhodococcus sp. |
24919140 |
| 3.1.1.84 | 716824 |
Structural analysis of thermostabilizing mutations of cocaine esterase |
Protein Eng. |
23 |
537-547 |
2010 |
Rhodococcus sp. |
20436035 |
| 3.1.1.84 | 716281 |
Subunit stabilization and pegylation of cocaine esterase improves in vivo residence time |
Mol. Pharmacol. |
80 |
1056-1065 |
2011 |
Rhodococcus sp. |
21890748 |
| 3.1.1.84 | 730250 |
The fate of bacterial cocaine esterase (CocE): An in vivo study of CocE-mediated cocaine hydrolysis, CocE pharmacokinetics, and CocE elimination |
J. Pharmacol. Exp. Ther. |
340 |
83-95 |
2012 |
Rhodococcus sp. |
21990608 |
| 3.1.1.84 | 694267 |
Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity |
Mol. Pharmacol. |
75 |
318-323 |
2009 |
Rhodococcus sp. |
18987161 |
| 3.1.1.84 | 699760 |
Zhan. C.G.; Woods. J.H.: Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats |
J. Pharmacol. Exp. Ther. |
331 |
445-455 |
2009 |
Rhodococcus sp. |
19710369 |
| 3.1.1.84 | 716276 |
A thermally stable form of bacterial cocaine esterase: a potential therapeutic agent for treatment of cocaine abuse |
Mol. Pharmacol. |
77 |
593-600 |
2010 |
Rhodococcus sp. MB1 |
20086035 |
| 3.1.1.84 | 730421 |
Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination |
Mol. Pharm. |
9 |
1361-1373 |
2012 |
Rhodococcus sp. MB1 |
22404344 |
