EC Number   |
Reaction |
Reference  |
|---|
   3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
- |
- |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
two-step mechanism involving an ester intermediate covalently bound at Asp124, His 289 is important for hydrolysis |
-, 247084, 247093 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
catalytic mechanism |
247086 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
GJ10, four-step reaction mechanism with covalent ester intermediate |
-, 247089, 247096 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
distinction of 3 different substrate classes for haloalkane dehalogenases after profound statistical reaction rate analysis |
-, 247090 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
alpha/beta hydrolase with catalytic triad, i.e. nucleophile (Asp124)-histidine (H289)-acid (Asp260), during catalytic reaction |
-, 247091, 247093, 247094, 247096, 247101 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
GJ10, three-step reaction mechanism with covalent alkyl-enzyme ester intermediate |
-, 247094 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
GJ10, detailed reaction mechanism and energetics calculated from computational model |
-, 247101 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
3 features are important for catalytic performance: i. a catalytic triad, ii. anoxyanion hole, and iii. the halide-stabilizing residues, which are not conserved among different haloalkane dehalogenases, active site structure, Asn38 is involved, SN2 reaction mechanism, modeling, overview |
-, 654629 |
| 3.8.1.5 | 1-haloalkane + H2O = a primary alcohol + halide |
3 features are important for catalytic performance: i. a catalytic triad, ii. anoxyanion hole, and iii. the halide-stabilizing residues, which are not conserved among different haloalkane dehalogenases, active site structure, Asn41 is involved, SN2 reaction mechanism, modeling, overview |
654629 |
